Prevention of Venous Thrombosis in Knee Arthroplasty

Abstract

Letters15 January 1997Prevention of Venous Thrombosis in Knee ArthroplastyLorne Basskin, PharmDLorne Basskin, PharmDButler University, Indianapolis, IN 46260Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-126-2-199701150-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:In a randomized, double-blind trial, Leclerc and colleagues [1] concluded that postoperative, fixed-dose exoxaparin is more effective than adjusted-dose warfarin in the prevention of deep venous thrombosis after knee arthroplasty. However, I do not believe that their conclusions and recommendations are justified.As a reference value, Leclerc and colleagues cited incidences of deep venous thrombosis without prophylaxis ranging from 55% to 70%. However, it is my understanding that these values relate to earlier years, in which the standard of care did not include early ambulation of the patient. Is it not possible that the incidence today, without ...REFERENCE1. Leclerc JR, Geerts WH, Desjardins L, Laflamme GH, l'Esperance B, Demers C, et al. Prevention of venous thromboembolism after knee arthroplasty. A randomized, double-blind trial comparing enoxaparin with warfarin. Ann Intern Med. 1996; 124:619-26. Google Scholar Author, Article, and Disclosure InformationAffiliations: Butler University, Indianapolis, IN 46260 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byLow-Dose Warfarin for Prevention of Symptomatic Thromboembolism after Orthopedic Surgery 15 January 1997Volume 126, Issue 2Page: 172-173KeywordsArthroplastyDeep vein thrombosisDrugsHeparinInternational normalized ratioKneesProphylaxisPulmonary embolismSurgeryWalking Issue Published: 15 January 1997 Copyright & PermissionsCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...