Prevention of venous thromboembolism through the implementation of a risk assessment tool: a comparative study in medical and surgical patients

Abstract

Hospitalized patients are at high risk of venous thromboembolism (VTE). Underutilization of thromboprophylaxis remains common despite existing clinical guidelines. The aim is to evaluate the implementation of a state wide standardized adult VTE risk assessment tool (RAT) to assist in the screening of inpatients and prescribing of appropriate thromboprophylaxis. In total, 234 patients were audited using clinical notes and spot assessments for VTE risk at Western Sydney Local Health District over a two year period. Patients were stratified into pre- (N.=132) and postimplementation (N.=102) of the RAT. Intervention involved continuing education of staff and passive dissemination of guidelines. Prescription of pharmacological and mechanical prophylaxis and the development of thromboembolic events were evaluated. Overall, 39.0% of medical and 63.0% of surgical patients were risk assessed during preimplementation versus 39.2% and 92.2% during postimplementation of the RAT (P<0.0001). Usage of pharmacological prophylaxis increased from 72% to 79% and mechanical prophylaxis from 41% to 48%. VTE rates in moderate to high risk medical patients decreased from 15.2% preimplementation to 6.5% postimplementation. Rates of non-fatal and fatal pulmonary embolism (PE) were 2.3% and 0.8% respectively prior compared to 1.0% and 0.0% postimplementation. Standardized VTE RAT increased thromboprophylaxis usage and decreased PE rates, with a greater improvement reflected in surgical patients. These findings highlight the importance of a multifaceted approach to VTE prevention using regular audits with feedback, electronic reminders systems, prescribing tools and continuing education.