Abstract
Live-attenuated varicella zoster virus (VZV) vaccines have been available for decades, but their potential to reduce disease worldwide has not been fully realised. Few countries have incorporated varicella vaccination into public programmes, even though rapid and large decreases in varicella deaths and admissions have been achieved in the USA and Australia.1,2 One reason for reluctance to vaccinate is that, despite high efficacy of 88–100% reported in the randomised controlled trials of one-dose live-attenuated monovalent varicella vaccines in children (Varilrix, GSK3 and Varivax, Merck4), field effectiveness has turned out to be lower at 72–81%.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.