Abstract
This article discusses the problems of rational pharmacotherapy in women with vulvovaginal atrophy developed after gynecological operations or during combination treatment for tumors of the female reproductive system. The range of adverse effects makes long-term treatment of these patients necessary not only to relieve the symptoms, but also to prevent possible problems, such as sexual dysfunction, postcoital bleeding, and recurrent urinary tract infections. Considering the pathogenesis of vulvovaginal atrophy associated with many unpleasant symptoms, such as dryness, burning, and dyspareunia resultedfrom low levels of estrogen, we have provided a rationale for topical application of Flamen® gel with subsequent restoration of vaginal pH. Effective relief of pain syndrome, which usually manifested itself with burning, itching, swelling, and hyperemia of the vaginal vestibule and perineal tissues, ensured maximum compliance during treatment and allowed the achievement of not only clinical, but also pathogenetic effect.
Highlights
This article discusses the problems of rational pharmacotherapy in women with vulvovaginal atrophy developed after gynecological operations or during combination treatment for tumors of the female reproductive system
Considering the pathogenesis of vulvovaginal atrophy associated with many unpleasant symptoms, such as dryness, burning, and dyspareunia resulted from low levels of estrogen, we have provided a rationale for topical application of Flamen® gel with subsequent restoration of vaginal pH
Естественная ранняя менопауза, связанная с овариальной недостаточностью Early natural menopause associated with ovarian insufficiency
Summary
Вагинальная болезненность, посткоитальное жжение, диспареуния, раздражающие бели, иногда кровянистые выделения Vaginal soreness, postcoital burning, dyspareunia, irritating white discharge, sometimes bloody discharge. Контактные дерматиты (гиперчувствительность с гормональным дисбалансом) Contact dermatitis (hypersensitivity with hormonal imbalance). Диспареуния, боль при введении тампона или вагинального расширителя у сексуально неактивных женщин, отечность промежности, иногда эритема. Усугубляются стрессом, тесной, неудобной одеждой, некачественными прокладками. Dyspareunia, pain when inserting a tampon or vaginal dilator in sexually inactive women, perineal edema, sometimes erythema. Symptoms are unstable, aggravated by stress, tight and uncomfortable clothing, poor-quality pads. Шампуни, дезодоранты, некоторые антисептики, лубриканты Soap, shampoos, deodorants, some antiseptics, lubricants
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