Abstract
IMMUNITY against homografts can be adoptively transplanted by cells from the regional lymph nodes or from the spleen1. This leads us to believe that antibodies produced by tissue incompatibility are produced only in these tissues. Extirpation of the regional nodes on the side of the graft only prolongs the survival of the homograft because of the temporary interruption of the lymphatic connexion2–5. According to Streicher and Herion, splenectomy in no way influences the survival of grafts6. In our experiments we investigated the survival-time of secondary grafts following extirpation of regional lymph nodes on the side of the primary graft, and following splenectomy.
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