Prevention of subclinical forms of ketosis and hypocalcemia in dairy cows

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Relevance. Against the background of stress and high physiological load, cows experience a lack of energy, the need for which increases many times over in comparison with the dry period, in connection with this, their body is forced to use the reserves of adipose tissue. It is important to timely prevent and monitor the status of cows during the transition period.Methods. The methodology of the work was to study the effectiveness of the use of immunostimulating drugs PS-2, Prevention-N-E and PDE + E-selen. For scientific research, 4 groups of down-calving cows of the Holsteinized Black-and-White breed were selected, 10 animals each. Dry cows of the 1st and 2nd experimental groups received PS-2 and Prevention-N-E intramuscularly at a dose of 10.0 ml three times (40, 20 and 10 days before calving), animals of the 3rd experimental group were injected subcutaneously with tissue preparation PDE (denatured emulsified placenta) at a dose of 20.0 ml and intramuscularly — with a complex mineral and vitamin preparation E-selen at a dose of 10.0 ml 20 days before calving. Biological preparations were not used in animals of the control group.Results. An analysis was made of the prevalence of postpartum metabolic disorders: clinically pronounced hypocalcemia was observed in 5.9% of the newly-calved cows, ketosis — in 11.6%, subclinical hypocalcemia — in 17.7%, and a latent form of ketosis — in 22.7%. Biological preparations PS-2 and Prevention-N-E have a corrective effect on the synthesis of aminotransferases, mineral and carbohydrate metabolism, digestibility of macronutrients, against which background the number of newly-calved cows with subclinical forms of ketosis and hypocalcemia is reduced by 2 times.