Abstract

There is still present, in the minds of many general practitioners, a doubt of the value of immunization against scarlet fever. In the New Jersey State Home for Boys, routine Dick tests are done on every boy admitted and all boys with a positive reaction are treated with Streptococcus scarlet fever toxin prepared according to the Dick method. Five doses, consisting of 500, 2,000, 8,000, 25,000 and 80,000 skin test doses, are given hypodermically at weekly intervals. The accompanying table gives the incidence of positive reactions in 3,025 Dick tests. All the tests during the last nine years were done by Dr. G. F. Leonard of the Biological Laboratories of E. R. Squibb & Sons, which eliminates a possible source of error. An intradermal injection of 0.1 cc. of standard scarlet fever toxin, containing one skin test dose, was given in each case and a reaction of 1 cm. or

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