Prevention of premature birth in pregnant women with vaginal candidiasis

Abstract

Candida vulvovaginitis is an infectious lesion of the vulvar and vaginal mucosa caused by Candida yeast fungi. Vaginal candidiasis during pregnancy is associated with spontaneous miscarriages, premature rupture of the fetal membranes, premature birth, and low birth weight babies. Considering the potential risk of premature delivery at fungal invasion at the level of the lower reproductive tract of a pregnant woman, the search for a complex of preventive measures and timely treatment of сandida vulvovaginitis during gestation is of particular interest. The article presents the results of the use of the drug Zalain in 36 pregnant women, with a gestation period of 28 weeks or more with acute candidal vulvaginitis. In the course of the work, the results of local therapy with Zalain were evaluated and its clinical efficacy in the prevention of preterm labor was confirmed. The results of treatment contribute to a significant reduction in the frequency of initiation of preterm labor, as well as a persistent effect for 2-4 weeks after completion of the course in the postpartum period and the absence of early and distant manifestations of candidiasis in newborns.