Abstract
SUMMARY The widespread use of non-phenolic sheep dips with low bacteriostatic properties has increased the need for suitable additives for the control of Erysipelothrix rhusiopatkiae, the causative organism of post-dipping lameness in sheep. An in vitro method for primary evaluation of candidate compounds has been developed, in which bacteriostats are tested in a laboratory-prepared simulated foul dip wash which can be sterilized and inoculated with the organism. Confirmatory tests are carried out in unsterilized wash, using mouse inoculation for recovery of surviving Erysipelothrix. Tetramethyl thiuram disulphide was selected by these tests and has since been used successfully in the field; the results it gave are cited as an example and the translation of laboratory findings into practical usage is discussed.
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