Prevention of oxaliplatin-induced peripheral neuropathy by a polyamine-reduced diet—NEUROXAPOL: protocol of a prospective, randomised, controlled, single-blind and monocentric trial

D Balayssac,B Pereira,J Ferrier,A Eschalier,F Libert,J Vein,D Pezet,B Gillet,C Petorin

doi:10.1136/bmjopen-2014-007479

Prevention of oxaliplatin-induced peripheral neuropathy by a polyamine-reduced diet—NEUROXAPOL: protocol of a prospective, randomised, controlled, single-blind and monocentric trial

D Balayssac, B Pereira + Show 7 more

Open Access

https://doi.org/10.1136/bmjopen-2014-007479

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Journal: BMJ Open	Publication Date: Apr 1, 2015
Citations: 18	License type: open-access

Affiliation: Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont Université, Inserm

#Oxaliplatin-induced Peripheral Neuropathy #Oxaliplatin-induced Peripheral Neuropathy In Patients + Show 8 more

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Abstract

IntroductionOxaliplatin remains the most widely used chemotherapeutic agent for treating advanced colorectal cancer but its efficacy is hampered by dose-limiting neurotoxicity manifested by a painful polyneuropathy. Oxaliplatin-induced peripheral neuropathy (OIPN)...

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