Abstract
In todays Lancet Janaki Amin and colleagues report on the causes of death after the diagnosis of hepatitis B and C infection in a community-based setting. The striking finding which comes as no surprise is that hepatocellular carcinoma (HCC) was the most common liver-related cause of death in those with chronic hepatitis B. Such patients are predisposed to HCC irrespective of the underlying histological severity. Similarly HCC was a common mode of death in hepatitis C patients but they usually had underlying cirrhosis. In both categories the risk of HCC could be significantly reduced by prevention of hepatitis B and C infections and early therapeutic intervention for those who already have chronic hepatitis. (excerpt)
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