Abstract
PYRIDINE, like dimethyl sulphide, forms a high-boiling, water-soluble oxide, pyridine N-oxide (PNO). It was surmised that PNO might protect living cells against freezing damage in the same way as dimethyl sulphoxide1 and some other aliphatic compounds2. The particular interest attached to PNO is that it would be the first aromatic compound to be used in this connexion.
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