Abstract
community-onset infections, in order to guide clinicians to select appropriate empirical antibiotics. Material and methods: A retrospective study was performed at medical wards of a district hospital at southern Taiwan between July 2009 and June 2011. Patients were included if they were more than 18 year-old, admitted via the emergent department, and their blood, sputum or urine culture revealed the growth of E. coli, K. pneumoniae, or P. mirabilis. From each patient only the first isolate from the infection site was included. Antimicrobial susceptibility was determined by the disc diffusion method. Results: Overall 827 patients were included, and 354 (42.8%) came from the community and 473 (57.2%) were referred from nursing home. Of the isolates acquired in nursing home, 45.5% (215/473) harbored ESBL. In contrast, 20.6% (73/354) isolates acquired in the community exhibited the ESBL production phenotype (P 90% Enterobacteriaceae isolates, irrespective of ESBL production. Conclusion: ESBL production was common among clinical Enterobacteriaceae isolates, esp. E. oli or those isolated from nursing home residents.
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