Prevention of breast cancer

Abstract

Objective. Breast cancer is the most common tumor in women. The purpose of this article is to find out the ways how to reduce the risk of breast cancer. Methods. The systematic review was based on PRISMA guidelines. Database was performed by using PubMed, Cochrane Library. There were analyzed 16 articles. Results. It was found correlation between the risk of breast cancer and the Mediterranean diet ((RR)=0.43, 95% confidence interval (CI)=0.21 to 0.88, n=1 study) (RR=0.92, 95% CI=0.87 to 0.96, n=16 studies); citrus fruits ((OR) = 0.90; 95% CI = 0.85–0.96; p < 0.001), cruciferous vegetables (RR = 0.85, 95% CI = 0.77–0.94), mushrooms (RR = 0.94, 95% CI = 0.91–0.97 for postmenopausal women; RR = 0.96, 95% CI = 0.91–1.00 for premenopausal women); physical activity (RR = 0.88, 95% CI = 0.85, 0.90); breast feeding (OR = 0.025); being ever pregnant (OR = 0.018). Conclusion. The main preventive methods of breast cancer are following Mediterranean and vegetarian diets, consumption of cruciferous vegetables, citrus fruits, soy, mushrooms and physical activity. Further research is needed.