Prevention effect of compound lidocaine cream and dyclonine mucilage as lubricant on laryngo-spasm in full-term neonates during general anesthesia of tracheal intubation surgery

Abstract

Objective To observe the prevention effect of compound lidocaine cream and dyc-loine mucilage as lubricant on larygospasm in full-term neonates during general anesthesia of tracheal in-tubation surgery. Methods Ninety ASA gradeⅠorⅡ full-term neonates,with body weight of 3 - 4 kg, scheduled for elective megacolon radical operation,were randomly divided into 3 groups（n = 30）：com-pound lidocaine cream（group L）,dyclonine mucilage（group D）and control group（group C）. The front end of tracheal catheters in group L was smeared with compound lidocaine cream uniformly before intuba-tion,and the front end of tracheal catheters in group D was smeared with dyclonine mucilage uniformly be-fore intubation,while the front end of tracheal catheters in group C was smeared with nothing before intuba-tion. At the end of the operation,the tolerance degree to the endotracheal tube and the incidence of laryn-gospasm was observed. Results Neonates in group L and group D were tolerated endotracheal tube better-ly than those in group C. The incidence of laryngospasm were significantly lower in group L and group D when compared with group C（P 〈0. 05）. Conclusions The front end of tracheal catheters smeared with compound lidocaine cream or dyclonine mucilage uniformly before intubation both can reduce the incidence of laryngospasm in full-term neonates during general anesthesia of tracheal intubation surgery. Key words: Compound lidocaine cream; Dyclonine mucilage; Full-term neonates; Laryngo-spasm; Prevention