Abstract
Scientists have increasingly sounded the alarm about insufficient global pandemic preparedness, messaging which has appropriately escalated in the past two decades after the SARS (Severe acute respiratory syndrome), MERS (Middle East respiratory syndrome), and Ebola outbreaks [1]. This global lack of readiness was revealed during the most recent COVID-19 pandemic via slow threat recognition, early mixed public health messaging, supply chain disruptions, and vaccine rollout challenges [2]. This article reviews how pandemic pathogens originate and describes methods of early pathogen detection. It also details how multi-level interventions such as public health messaging, widespread accessible testing, and international cooperation, including funding, are critical tools for mitigating the spread of disease. Finally, we discuss how advancements in biotechnology help counter widespread outbreaks, including the use of early molecular diagnostics, application of therapeutics, and the development of "plug and play" vaccines. The world demands early and strong preparation to prevent the next pandemic.
Highlights
Scientists have increasingly sounded the alarm about insufficient global pandemic preparedness, messaging which has appropriately escalated in the past two decades after the SARS (Severe acute respiratory syndrome), MERS (Middle East respiratory syndrome), and Ebola outbreaks [1]
Laboratory studies provide valuable information for human infection potential and may translate to preclinical evidence for the development of therapies. These anticipatory investigations allow for timely interventions and early, sophisticated understanding of mechanisms that may help halt the spread of emerging pathogens of pandemic potential
Improvements and adherence to public health measures, widespread accessible testing, and clear communication to the public are indispensable tools for intercepting infections and preventing pandemic spread. Public health measures such as quarantines, travel restrictions, wearing masks, and universal screening of healthy individuals indisputably slow the spread of pandemics [35]
Summary
Scientists have increasingly sounded the alarm about insufficient global pandemic preparedness, messaging which has appropriately escalated in the past two decades after the SARS (Severe acute respiratory syndrome), MERS (Middle East respiratory syndrome), and Ebola outbreaks [1] This global lack of readiness was revealed during the most recent COVID-19 pandemic via slow threat recognition, early mixed public health messaging, supply chain disruptions, and vaccine rollout challenges [2]. This article reviews how pandemic pathogens originate and describes methods of early pathogen detection It details how multi-level interventions such as public health messaging, widespread accessible testing, and international cooperation, including funding, are critical tools for mitigating the spread of disease. The world demands early and strong preparation to prevent the pandemic
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