Abstract
Goal of the study. To study the prevalence of syphilis markers in donors in the Russian Federation, and to evaluate the effectiveness of measures to prevent blood transfusion syphilis and other bloodborne infections in the Blood Service in Russia. Materials and methods. Performance analysis of sectoral statistical surveys Russian Ministry of Health in the form number 39, «Report of the station, department of blood transfusion, hospital blood leading procurement» and the explanatory notes to them for the period from 2009 to 2013. Analysis of the results of screening donated blood for markers of syphilis. Results. It was found that the incidence of syphilis markers in donors in the whole of Russia was significantly (p < 0,05) decreased (from 0.79% in 2009 to 0.49% in 2013). However, there was heterogeneity in the proportion of donors with markers of syphilis in different regions of the Russian Federation. (From 0.68 to 0.35%). In 2013, the causative agent of syphilis markers are more often detected in donors of the North Caucasus and Siberian Federal Districts, seldom in donors in the North-Western and Urals Federal District. Hence, there remains a certain risk of transfusion transmission of syphilis. In recent years, widely implemented method viral inactivation of plasma and platelet concentrate. In 2013, the procedure viral inactivation subjected to 8% of the total issued for transfusion platelet concentrate. Conclusion. There remains a certain risk of transfusion transmission of syphilis. Further implementation of the methods of inactivation of pathogens in Blood Service of Russia will also contribute to reducing the risk of blood-borne transmission of Treponema pallidum.
Highlights
It was found that the incidence of syphilis markers in donors in the whole of Russia was significantly (p < 0,05) decreased
In 2013, the causative agent of syphilis markers are more often detected in donors of the North Caucasus and Siberian Federal Districts, seldom in donors in the North-Western and Urals Federal District
There remains a certain risk of transfusion transmission of syphilis
Summary
Изучить распространенность маркеров сифилиса у доноров в Российской Федерации и оценить эффективность мероприятий по профилактике гемотрансфузионного сифилиса и других гемотрансмиссивных инфекций в службе крови России. Анализ результатов скрининга донорской крови на маркеры возбудителя сифилиса. Установлено, что частота выявления маркеров сифилиса у доноров в целом по РФ достоверно (p < 0,05) снижалась Однако выявлена гетерогенность доли доноров с маркерами сифилиса в разных регионах Российской Федерации (от 0,68 до 0,35%). Поэтому сохраняется определенная опасность гемотрансфузионной передачи сифилиса. В последние годы широко внедряется метод вирусинактивации плазмы и тромбоцитного концентрата. Процедуре вирусинактивации подвергалось 8% всего выдаваемого для трансфузий тромбоцитного концентрата. Дальнейшее внедрение методов инактивации патогенов в практику работы учреждений службы крови России будет способствовать также снижению опасности гемотрансмиссивной передачи Treponema pallidum.
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