Abstract
The goal of the programme was to achieve a 7% reduc-tion in body weight and physical activity of moderateintensity for at least 150 minutes per week. The cumula-tive incidence of diabetes was 4.8, 7.8 and 11.0 cases per100 person-years in the lifestyle, metformin and controlgroups, respectively. This reduction in incidence equatedto one case of diabetes prevented for every seven peoplewith IGT treated for three years in the lifestyle interven-tion group, compared with 14 for the metformin group. In addition, a review has also indicated that the numbersneeded to treat (NNT) to prevent one case of type 2 dia-betes with lifestyle intervention in people at risk of diabetesis dramatically low at 6.4 (over 1.8 to 4.6 years).
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