PREVENTATIVE EFFECTS OF PROBIOTIC (MIACLOST) ON EXPERIMENTALLY INDUCED HYPOCALCEMIC RICKETS IN BROILER CHICKS.

A H Hassan,N A Ameen,N R Abdul Rahman

doi:10.36103/ijas.v52i6.1487

Abstract

A trial was conducted to study the effects of probiotic (Miaclost) supplement on experimentally induced hypocalcemic rickets in broiler chicks, a total of 180 one-day-old broiler chicks (Ross 308) were randomly divided into three equal groups 60 chicks per group with 3 replicates (20 birds /replicate) the dietary treatments consisted of a normal ration for G1, calcium-deficient ration 5% for G2 and calcium-deficient ration with addition of probiotics in drinking water for G3.Initial signs of rickets have been observed at 35-day of age in G2.while, in G1 and G3 no clinical signs observed, the gross lesions appeared enlargement of parathyroid gland, costochondral junction and increase in the width of growth plate of tibial bone of G2 whereas no gross lesions recorded in G1 and G3, the histopathological examination of parathyroid gland in G2 there were a focal parathyroid hyperplasia and increasing in numbers of syncytial cells and normal in G1 and G3, no intestinal histopathological changes in G1 and G2 and increase in height and width of the intestinal villi in probiotic group G3. Marked increase in the thickness of proliferation zone within growth plate of tibia bone in G2 and normal thickness in G1 and G3. the serum biochemical analysis of calcium of G2 recorded significantly low level in G2 and high level in G3 comparatively with G1, finally the serum alkaline phosphatase values were high significantly in G2 and normal in G3, it is concluded that probiotic (MiaClost) can be used as prophylaxis to prevent hypocalcemic rickets in broiler chicks

Highlights

Producers of broiler chicks started use antibiotics as feed additives to increase the digestive system performance of broiler chickens, they are mainly used to prevent infections, treat infected animals and to stimulate growth [22]
Pro. (MiaClost) was as efficient as antibiotics in controlling efficiency, including the ratio of body weight gain and feed conversion, and improving gut integrity by raising Villus Height and Villus Height: Crypt Depth ratio in broiler chicks threatened by E Coli, suggesting that MiaClost can act as a substitute for antibiotics to suppress E coli infection [29]
In the gastrointestinal (GI) tract, these microorganisms compete with ingested pathogens, generate volatile fatty acids and stimulate immune responses to foreign microorganisms [7], Display inhibition action against bacterial infections (Staphylococcus aures, Pseudomonas aeruginosa) [39], [26] showed that the presence of active compounds in chamomile including that may act like pro

Summary

INTRODUCTION

Producers of broiler chicks started use antibiotics as feed additives to increase the digestive system performance of broiler chickens, they are mainly used to prevent infections, treat infected animals and to stimulate growth [22]. From one day old the chicks in G2 received ration deficient in calcium without MiaClost pro. RESUITS AND DISCUSSION Generally, at the end of each week (1, 2, 3 and 4) of the chickens age there were no changes or statistical significant differences recorded of all studded parameters between the groups of the experiment, while, following this period the pathological changes were start to observed and there were a significant differences at (P

Groups a

Findings

Impact of Probiotics on the Gastrointestinal