Abstract
This was a study on the prevalence of HIV-syphilis coinfection among 830 HIV/AIDS patients who were being followed up as outpatients at a hospital in Rio de Janeiro between January and May 2005. The participants underwent laboratory tests at the venereal disease research laboratory (VDRL) consisting of CD4+/CD8+ cell counts and viral load tests. They answered questions about their sociodemographic characteristics and past medical history of syphilis. The prevalence of syphilis was 2.7% (22 patients) and the ratio between men and women with coinfection was approximately 4:1. Homosexual men were the category most affected. We did not find any association between coinfection and age, schooling and the laboratory parameters tested. Out of the total number of patients with syphilis, 73% (16) reported previous treatment; of these, 14 (88%) were reinfected, while two (12%) underwent inappropriate treatment. The presence of HIV-syphilis coinfection among patients undergoing routine follow-up signals the need to advise them to adopt safe sex practices, during their outpatient visits.
Highlights
Resumo Estudo de prevalência da co-infecção HIV-sífilis realizado com 830 pacientes em acompanhamento ambulatorial para HIV/aids entre janeiro e maio de 2005 no Hospital na cidade do Rio de Janeiro
This was a study on the prevalence of HIV-syphilis coinfection
We did not find any association between coinfection and age
Summary
Foi realizado um estudo transversal em 830 pacientes infectados pelo HIV/aids, com idade mínima de 13 anos, em acompanhamento ambulatorial no Hospital Universitário na cidade do Rio de Janeiro, entre janeiro a maio de 2005. Todos os pacientes participantes do estudo assinaram o termo de consentimento e realizaram os exames VDRL (Veneral Disease Research Laboratory), contagem de células CD4+, CD8+. As estimativas odds ratio (OR) dos fatores determinantes para o diagnóstico da sífilis foram feitas através de análise de regressão logística, utilizando sexo (homens/mulheres), categoria de exposição (homossexuais/outras categorias) e idade (contínua), como, variáveis independentes. Dos 830 exames de VDRL realizados, houve uma perda de 8, devido a extravio do resultado pelo laboratório, sendo o total de indivíduos estudados para co-infecção HIV-sífilis de 822 pacientes. VDRL Negativo 1/1 1/2 1/4 1/6 1/8 1/12 1/16 1/32 1/64 1/128 1/256 VDRL: veneral disease research laboratory
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