Abstract

Older subjects have a high risk of developing zinc and copper deficiencies.To determine the prevalence of copper and zinc deficiencies in adults aged over 60 years, living in Metropolitan Santiago.Analyses were performed using anonymous serum samples from older subjects living in Santiago, Chile, who participated in the multicenter project SABE. Of the studied subjects, 49.3% had enough left over serum to measure serum zinc and copper concentrations by atomic absorption spectrometry.A total of 444 men and 198 women were studied. A positive correlation between serum zinc and copper was found in both women (r = 0.44, p < 0.001) and men (r = 0.48, p < 0.001). There were no differences in serum zinc concentration by sex and age. The prevalence of subnormal serum zinc valúes was 66.9% in women and 66.7% in men. Women had a significantly higher serum copper valúes than men (p < 0.02) and there were no differences by age. Prevalence of subnormal serum copper valúes was higher in women than in men (32.9 and 23.7% respectively, p < 0.05). Women had significantly higher copper I zinc serum ratio than men (p < 0.001).Older people living in Metropolitan Santiago have a high prevalence of copper and zinc deficiencies.

Highlights

  • Older subjects have a high risk of developing zinc and copper deficiencies

  • Aim: To determine the prevalence of copper and zinc deficiencies in adults aged over 60 years, living in Metropolitan Santiago

  • Subjects and Methods: Analyses were performed using anonymous serum samples from older subjects living in Santiago, Chile, who participated in the multicenter project SABE

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Summary

Background

Older subjects have a high risk of developing zinc and copper deficiencies. Aim: To determine the prevalence of copper and zinc deficiencies in adults aged over 60 years, living in Metropolitan Santiago. Women had a significantly higher serum copper values than men (p < 0.02) and there were no differences by age. Prevalence of subnormal serum copper values was higher in women than in men (32.9 and 23.7% respectively, p < 0.05). Women had significantly higher copper/zinc serum ratio than men (p < 0.001). El zinc (Zn) y el cobre (Cu) poseen importantes funciones en el organismo ya que son necesarios para la función de numerosas enzimas. Existe escasa información nacional y regional sobre la prevalencia de deficiencias de zinc y cobre en adultos mayores, especialmente de este último mineral. El propósito del estudio es determinar la prevalencia de las deficiencias de zinc y cobre en adultos de 60 años y más de la Región Metropolitana de Santiago de Chile

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