Abstract
Background: Vitamin D status of Thai patients receiving renal replacement therapy (RRT) is incompletely known. Objectives: To determine the prevalence of vitamin D deficiency or insufficiency in adult Thai patients receiving various RRT modalities, and factors associated with low vitamin D levels. Methods: In this retrospective, observational, single-center, cross-sectional study, we evaluated dialysis-related laboratory test variables from 111 patients receiving RRT. Serum 25-hydroxyvitamin D concentration [25(OH)D] Results: Low vitamin D levels were identified in 100% patients receiving peritoneal dialysis (PD; 81% deficient, 19% insufficient), 94% patients receiving online-hemodiafiltration (OL-HDF; 50% deficient, 44% insufficient), and 100% patients with kidney transplants (KT; 55% deficient, 45% insufficient). PD patients showed significantly lower serum [25(OH)D] than OL-HDF or KT patients (10.5 ± 5.9 vs 17.7 ± 8.5 vs 15.4 ± 6.1 ng/mL respectively, P Conclusions: Nearly 100% patients receiving RRT had vitamin D deficiency or insufficiency, and RRT modalities might be related. Keywords: prevalence, renal replacement therapy, vitamin D deficiency, 25 hydroxyvitamin D
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