Abstract

Prevalence of UTI in HIV patients is well documented in several studies across the world, but there is paucity of data as regards UTI in HIV patients in Jos metropolis, Nigeria. The study was designed to determine the prevalence of urinary tract infection in HIV positive patients in Jos metropolis and their antibiotic susceptibility pattern. Two hundred and twenty-five mid-stream urine samples were obtained from HIV patients. Samples were cultured on cysteine lactose electrolyte deficient (CLED) agar and blood agar. Gram staining and biochemical tests were carried out to identify the bacteria isolates. Sensitivity testing was performed on isolates using disc diffusion method. Of the 225 HIV patients tested, 13(5.8%) were positive for UTI of which males had 5(4.8%) while the females had 8(6.6%). The study showed the presence of UTI in all age groups with the exception of age group ≥46yrs. The low prevalence of urinary tract infection recorded in the present study is an indication of the efficacy of prophylaxis administered to HIV patients to prevent opportunistic infection.

Highlights

  • Urinary tract infection is one of the most common bacterial infections and the cause of morbidity and hospitalization in HIV positive individuals

  • Several studies have shown that the prevalence and risk of urinary tract infection (UTI) among HIV infected patients may be significantly high in HIV infected patients mainly with CD4 cell counts < 200 cells/ μL [2]

  • There have been several studies on this subject and it is expected that the stakeholders involved in management of HIV positive individuals have utilized the result emanating from previous study, the low prevalence observed in this study

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Summary

Introduction

Urinary tract infection is one of the most common bacterial infections and the cause of morbidity and hospitalization in HIV positive individuals. Urinary tract infection is responsible for approximately 60.0% of opportunistic infections associated with AIDS. This represents a considerable health problem amongst HIV infected patients [1]. A complicated UTI is that which occurs in a patient with an abnormal anatomical urinary tract [4], while uncomplicated UTI refers to the occurrence of bacterial infection in patients with normal structural and functional urinary tract [5]. Recent studies have demonstrated a broad range of microorganisms causing UTIs in HIV-infected patients, namely Escherichia. This study was set out to determine the prevalence of urinary tract infection among HIV positive individuals

Study Area
Ethical Consideration
Specimen Collection
Sample Processing and Culture
Antibiotic Susceptibility Testing
Results
Discussion
Conclusion
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