Prevalence of Typhoid Fever in Kathmandu Valley and Its Rapid Diagnosis by Detection of IgM Antibodies, Using Commercial Kit

Abstract

(PCT) and its effects and important for quickly distinguishing between bacterial and viral infections in children and infants Results: We found that the procalcitonin (PCT) concentrations increases in bacterial infections but remains low in viral infections and inflammatory diseases. The change is rapid and molecule is stable, making it as potentially useful marker for distinguishing between bacterial and viral infections. Discussion: Its advantages over CRP, IL-6 and INF alpha are clear but it doesn’t mean that those methods, despite some disadvantages earlier explained, should be rejected. Comclusions: PCT may be useful in an emergency room for differentiation of bacterial from viral infections in children and for making decisions about antibiotic treatments. The change is rapid and the molecule is stable, making it a potentially useful marker for distinguishing between bacterial and viral infections. Comparing PCT with CRP (C reactive protein), interleukin 6, and interferon alpha demonstrates increased values for PCT than for the others for and thus may be better for differentiation between bacterial and viral infections.