Abstract

e12561Background: The prevalence of triple negative breast cancer (TNBC) is reported to be higher in India than observed in western population. There is substantial variation in prevalence rates be...

Highlights

  • Breast cancer is a heterogeneous disease with different biologic subtypes that are recognized by gene expression profiling studies

  • These subtypes are characterized on the basis of expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2)

  • Prevalence of Triplenegative breast cancer (TNBC) in India is reported to be higher than that observed in Western populations; there is considerable variation in prevalence rates reported by studies from the region

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Summary

Introduction

Breast cancer is a heterogeneous disease with different biologic subtypes that are recognized by gene expression profiling studies. These subtypes are characterized on the basis of expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). 80% in Western countries.[8] Whereas breast cancer incidence seems to be increasing in the country, epidemiology of the disease is inadequately studied.[9] Prevalence of TNBC in India is reported to be higher than that observed in Western populations; there is considerable variation in prevalence rates reported by studies from the region.

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