Prevalence of salivary gland neoplasms in the head and neck in educational hospitals in Cairo Governorate

Abstract

Background: Salivary gland neoplasms are morphologically diverse neoplasms with variable histology, clinical behavior, and tumor grade. Moreover, specific gene translocations and fusions are associated with some types of SGNs. Aim: To evaluate the prevalence of salivary gland neoplasms diagnosed in Cairo's educational hospitals and to compare the results with findings in the literature. Materials and Methods: Data of salivary gland neoplasms diagnosed between 2010 and 2019 were collected from the files of the Cairo's educational hospitals. Results: Salivary gland neoplasms in the present study constituted 2.4% of all the 9609 registered oral and maxillofacial biopsies. A total of 231 cases of SGNs were collected and reviewed. Of these, (61.1%) were benign and (38.9%) were malignant. Minor salivary glands (51.94%) were more involved than major ones (45.02%). Pleomorphic adenoma was the most frequent type of benign SGNs (68.8%) while Mucoepidermoid carcinoma was the most frequent type of malignant SGNs (46.7%). The mean age of SGNs was 41.14 ±15.43 years with a slight male predilection. Conclusion: In this study we observed a marked geographic variation in the relative frequency of various salivary gland neoplasms in Cairo government.