Abstract
Introduction Background : restless legs syndrome (RLS) is affecting the quality of sleep and is encountered in many diseases. There are few data on the prevalence of restless legs syndrome (RLS) in chronic liver diseases (CLD). The purpose of this pilot study was to assess the prevalence and clinical features of RLS in chronic liver diseases patients in a case-control study. Materials and methods Prospective study on 90 patients with chronic liver diseases and 90 healthy volunteers, age and sex matched. RLS was diagnosed using the criteria of the International RLS Study Group, severity by International RLS Study Group Rating Scale. For quality of sleep and depression assessment we used Restless Legs Syndrome Quality of Life instrument, Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index, Hospital Anxiety and Depression Scale. Results 35/90 (38.88%) patients with chronic liver diseases fulfilled the 4 criteria for RLS vs.11/90 (12,22%) in the control group ( p Conclusion RLS symptoms have a high prevalence in chronic liver disease and affect quality of sleep.
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