Abstract

Background. Peripheral arterial disease (PAD) is a common manifestation of atherosclerosis, whose prevalence is increasing worldwide, and is associated with all-cause mortality. However, no study has assessed this disease in Huambo. The aim of this study was to evaluate the prevalence of PAD in patients attending an outpatient clinic at a general hospital in Huambo, South Angola. Methods. A cross-sectional study, including 115 patients aged 40 years and older attending an outpatient service. The evaluation included a basic questionnaire for lifestyle and medical history and ankle-brachial index (ABI) measurement using hand-held Doppler. PAD was defined as an ABI ≤0.9 in either lower limb. Results. Of 115 patients, 62.60% were women with a median age of 52.5 (range of 40 to 91) years. The prevalence of PAD was 42.6% (95% confidence intervals [CI]: 95%: 33.91–52.17%). Among patients with PAD, 95.92% had mild disease and 4.08% moderate to severe disease. The main risk factor for PAD was age (≥60 years) (χ 2 = 3.917, P ≤ 0.05). The prevalence was slightly higher in men and hypertensive subjects, but without statistical significance with ORs of 1.5 (95% CI: 0.69–3.21) and 1.42 (95% CI: 0.64–3.17), respectively. Hypertension was also high in the group (66.95%). Conclusion. The prevalence of PAD was 42.6%, higher in those aged 60 years and older. More studies, with representative samples, are necessary to clarify PAD prevalence and associated risk factors.

Highlights

  • Peripheral arterial disease (PAD) is an important manifestation of atherosclerosis, which in 2010 was estimated to affect more than 202 million people worldwide [1]

  • The prevalence of peripheral arterial disease (ABI ≤ 0.9) was 42.6% (n = 49; 95% CI: 33.91–52.17%) (Figure 1); and nobody had an ankle-brachial index (ABI) value >1.3

  • There was no significant association between PAD and hypertension (OR: 1.42; 95% CI: 0.64–3.17) or male sex (OR: 1.5; 95% CI: 0.69– 3.21) (Table 2 and Figure 1)

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Summary

Introduction

Peripheral arterial disease (PAD) is an important manifestation of atherosclerosis, which in 2010 was estimated to affect more than 202 million people worldwide [1]. From 2000 to 2010, the number of people with the disease increased by 28.7% and 13.1% in low- and high-income countries, respectively [1] It affects about 4.3% of Americans aged 40 years and older [2], reaching 12.29% and 29% in those over 60 and 70 years of age, respectively [3, 4]. The main risk factors are advanced age (>65 years), smoking, diabetes, hypertension, and chronic kidney disease [3, 15, 16]. Peripheral arterial disease (PAD) is a common manifestation of atherosclerosis, whose prevalence is increasing worldwide, and is associated with all-cause mortality. A cross-sectional study, including 115 patients aged 40 years and older attending an outpatient service. With representative samples, are necessary to clarify PAD prevalence and associated risk factors

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