Abstract

The burden of head and neck squamous cell carcinoma (HNSCC) is increasing globally with 600,000new cases being reported annually. A great proportion of these are oral squamous cell carcinomas (OSCCs) which are preceded by oral potentially malignant disorders (OPMDs). The aim of our study was to assess the prevalence of OPMDs among adult Malaysian dental patients with and without risk habits. The objectives of this study were i) to determine the prevalence of OPMDs among dental patients who were tobacco smokers ii) to determine the prevalence of OPMDs among dental patients who were alcohol users iii) to determine the prevalence of OPMDs among dental patients without any risk habits iv) to determine the awareness on oral cancer among dental patients with and without risk habits. Materials and methods: This was a cross sectional observational study, carried out at Faculty of Dentistry, University of Malaya. A conventional oral examination was conducted by two investigators who were trained and calibrated prior to the survey. Participants were administered a questionnaire that was pre-tested in a previous study. 83 subjects were recruited into the study. Leukoplakia was the only OPMD detected in our study with a prevalence of 10.8%. All patients diagnosed with leukoplakia were males (P < 0.05). A significant association between the prevalence of OPMDs and risk habits was found. There was a general lack of awareness among smokers regarding alcohol as an aetiological agent for oral cancer. A significant proportion of subjects who smoked were unaware of early signs of oral cancer.

Highlights

  • The prevalence of oral mucosal lesions (OML) in different populations shows a great variability

  • There was a general lack of awareness among smokers regarding alcohol as an aetiological agent for oral cancer

  • Environmental stresses such as smoking, alcohol drinking and betel-quid chewing play a critical role in causing OPMD and OSCC when we reviewed the literature dealing with CNAs that drive oral precursor lesions to the invasive tumors

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Summary

Introduction

The prevalence of oral mucosal lesions (OML) in different populations shows a great variability. Reports about the prevalence of OML are based on studies on different populations such as the elderly, children, and patients visiting dental schools, college students, hospitalized patients, misusers and normal population[1]. Such surveys provide an accurate description of the epidemiology of OML. In Malaysia, several surveys of OML targeting specific subject groups have been carried out. These include reports on the prevalence of selected OMLs among Indians and Malays, in an army population and among the older age groups. A national epidemiological survey of OML in Malaysia reported the prevalence of OML to be 9.7%(2)

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