Abstract
Human papillomavirus (HPV) causes cervical, head, and neck cancers. We studied 483 patients at a youth clinic in Stockholm, Sweden, and found oral HPV prevalence was 9.3% and significantly higher for female youth with than without cervical HPV infection (p = 0.043). Most oral HPV types matched the co-occurring cervical types.
Highlights
Human papillomavirus (HPV) causes cervical, head, and neck cancers
A 10-μL aliquot for each sample was analyzed for 24 mucosal HPV types by using a Luminex-based multiplex assay, as described by Schmitt et al [6], using a MAGPIX instrument (Luminex Corporation, Austin, TX, USA)
Oral HPV infection was more frequent in female youth with (22/129, 17.1%) than without (2/45, 4.4%) cervical HPV infection (p = 0.043)
Summary
We studied 483 patients at a youth clinic in Stockholm, Sweden, and found oral HPV prevalence was 9.3% and significantly higher for female youth with than without cervical HPV infection (p = 0.043). To evaluate oral HPV prevalence before HPV vaccination of the public, we performed a study at a youth clinic in Stockholm, Sweden, where we previously reported high cervical HPV prevalence (70%) among female youth [5]. We compared oral HPV prevalence in male and female youth visiting the clinic and studied oral HPV prevalence and type concordance in relation to cervical HPV infection.
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