Prevalence of obstructive sleep apneas in patients with idiopathic interstitial pneumonia

Abstract

Background: Increasing attention has been focused on the prevalence of obstructive sleep apnea (OSA) in patients with idiopathic pulmonary fibrosis (IPF). Recent studies showed a prevalence of OSA in IPF subjects between 59% and 90%, higher than reported in healthy age-matched populations. Objectives: To determine the prevalence of OSA in a group of patients diagnosed with IPF. Materials and Methods: An observational retrospective study was conducted. Data from the medical records of all patients diagnosed with IPF who had polysomnography requested as part of the study protocol in patients with IPF were collected. Patients were classified as normal (AHI Results :36 patients, 26 men (72.3%) were included. The mean age was 67.5±6.4 years. Mean FVC was 2.1±0.8 l and 61.9%±15.8 in percentage of predictive. The mean BMI was 28.8±4.2. The ESE average was 7.5±5 and the mean AHI 12.7±19.4. Of the total 17 (47.2%) patients had OSA, of these, 9 (25%) had AHI≥10. Comparing groups of patients with and without OSA we could not find statistically significant differences. In the group of patients with OSA (n=17), 9 (52.9%) had an AHI between 5 and 15, and 8 (47%) a AHI≥15. Discussion: Consistent with previous findings we found no significant differences comparing the IAH with ESE. We found no statistically significant relationship between the parameters of the PSG (IAH and CT90) and BMI (r 0.31 and r 0.39). Conclusions: In our serie we found a prevalence of OSA of 47.22%. No correlation between ESE and the BMI and the presence of OSA in patients with IPF, which both would be a poor screening tool was established.