Abstract
Incidence of pulmonary infection with nontuberculous mycobacteria (NTM) is increasing among persons with cystic fibrosis (CF). We assessed prevalence and management in CF centers in the United Kingdom and found 5.0% of 3,805 adults and 3.3% of 3,317 children had recently been diagnosed with NTM. Of those, 44% of adults and 47% of children received treatment.
Highlights
Incidence of pulmonary infection with nontuberculous mycobacteria (NTM) is increasing among persons with cystic fibrosis (CF)
Since the 1990s, NTM have been increasingly isolated from the sputum of patients with cystic fibrosis (CF) [7,8]
A multicenter CF study in France reported a prevalence of 6.6%, showing M. abscessus complex (MABSC) to be the most common; Mycobacterium avium complex (MAC) was the most prevalent [10]
Summary
Incidence of pulmonary infection with nontuberculous mycobacteria (NTM) is increasing among persons with cystic fibrosis (CF). Since the 1990s, NTM have been increasingly isolated from the sputum of patients with cystic fibrosis (CF) [7,8]. A multicenter prospective study of CF patients in the United States [9] found the prevalence of NTM in sputum to be 13%; MAC was the most common species (72%), and M. abscessus was the most common (16%).
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