Abstract

BackgroundNocturia is widely prevalent condition with detrimental effects on quality of life and general health. In Malaysia, there is a lack of up-to-date prevalence study on nocturia. This study aimed to investigate the prevalence of nocturia and awareness pertaining to nocturia among Malaysian adults.MethodsA cross-sectional population-based study was conducted among Malaysian adults aged ≥ 18 years old. The data was collected by mixed mode self-administered questionnaire from May 2019 to September 2019. Nocturia was defined as one or more voids at night.ResultsThere were a total of 4616 respondents with 74.5% of response rate. The overall prevalence of nocturia among Malaysian adults was found to be 57.3%. In multivariate analysis, respondents aged 31–40 (1.91 [1.52–2.40]) or > 60 years old (2.03 [1.48–2.71]), and those who presented with hypertension (2.84 [2.28–3.53]), diabetes mellitus (1.78 [1.42–2.25]), renal disease (3.58 [1.93–6.63]) or overactive bladder (1.61 [1.10–2.35]) were associated with higher prevalence of nocturia. A significantly lower disease prevalence (p < 0.05) was noted among those aged 41–50 (0.73 [0.59–0.91]), male (0.78 [0.69–0.88]) and Chinese (0.47 [0.30–0.74]) or Indian (0.34 [0.21–0.54]) ethnicities. A total of 37.3% of respondents with nocturia reported that they faced sleeping difficulty about half the time or more after waking up in the middle of night. Those who had ≥ 2 voids per night experienced significantly higher mean bother score than those who had 1 void per night (p < 0.001). Approximately half (56.7%) of all respondents were not aware that night time urination is a medical condition. Only 25.2% of respondents with nocturia had sought medical attention for their nocturia.ConclusionsThe prevalence of nocturia among Malaysian adults is high and strongly influenced by age, sex, race and comorbidities. However, the general awareness pertaining to nocturia being a health issue remains low among Malaysians. The findings also highlighted the impact of nocturia on sleep and the need for nocturia education to better address this disease.

Highlights

  • Nocturia is widely prevalent condition with detrimental effects on quality of life and general health

  • Full list of author information is available at the end of the article

  • The overall prevalence of nocturia among Malaysian adults was 57.3% (Table 2), with 34.1%, 15.3% and 7.9% having an of an average of one void per night, two voids per night and three or more voids per night respectively

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Summary

Introduction

Nocturia is widely prevalent condition with detrimental effects on quality of life and general health. Bosch and Weiss reviewed the nocturia prevalence studies in community based, predominantly populations in the western countries and some Asian countries (including China, Taiwan, Japan, Korea, Hong Kong and Singapore) [3]. They reported that prevalence of nocturia among younger populations (20–40 years old) with one or more voids per night varies from 11–44% whilst those with two or more voids per night has been reported to range between 2–18% [3]. A longitudinal study conducted by van Doorn and colleagues in the Dutch municipality Krimpen aan den IJssel showed that the prevalence of nocturia increases over time and with increasing age among men aged 50 to 78 years [4]

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