Abstract
ABSTRACT The occurrence of multidrug-resistant (MDR) bacteria in groundwater samples from Osogbo, southwest Nigeria was investigated in this study. Bacteria isolated from the water samples were tested against antibiotics by disc diffusion method. Out of the 113 gram-negative bacteria isolated, E. coli (28.32%) was the most predominant and the least was Serratia spp. (2.65%). All the isolates were 100% resistant to cefuroxime and <20% susceptible to ceftazidime and cefixime. More than 99% of the isolates were MDR and 33 (29.20%) were resistant to at least five classes of antibiotics. High prevalence of MDR bacteria in the groundwater indicates that the water sources are reservoirs of antibiotic resistance.
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