Abstract
BackgroundAntibiotic resistance is associated with longer hospitalizations, higher treatment costs, and increased morbidity and mortality rates.PurposeThis study aimed to determine the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in Iranian children.MethodsInternational databases, including Web of Science, PubMed, Embase, and Scopus, and Iranian databases, including Scientific Information Database (www.sid.ir), Magiran, and Iranian Database for Medical Literature (idml.research.ac.ir), were systematically searched for articles published between January 2000 and August 2019. Sources of heterogeneity were determined using subgroup analysis and meta-regression.ResultsOverall, 343 studies were identified; of them, 20 were included in the meta-analysis to estimate the pooled prevalence. The pooled prevalence of MRSA was 42% (95% confidence interval [CI], 29–55) among culture-positive cases of S. aureus, 51% (95% CI, 39–62) in hospitalized children, and 14% (95% CI, 0.05–27) in healthy children.ConclusionThe overall pooled prevalence of MRSA in children was 42%. Appropriate infection control measures and effective antibiotic therapy are needed.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
