Prevalence of metabolic syndrome and its components among a population-based study in south of Iran, PERSIAN Kharameh cohort study

Abstract

Objectivesover the past few years, lifestyle modification has increased the prevalence of major components of metabolic syndrome (MetS), leading to increased risk of non-communicable diseases, especially cardiovascular disease. The present study was aimed to determine the prevalence of MetS and its components and present results according to the major demographic characteristics of the participants in a population-based study. MethodsThis cross-sectional study was conducted on a total of 10663 subjects aged 40–70 years who participated in phase one of PERSIAN Kharameh cohort carried out between 2014 and 2017. ResultAccording to IDF, ATP III, and an Iranian definition, the prevalence of MetS were reported as 37.00%(36.08–37.92), 33.82% (32.93–34.73), and 33.13% (32.24–34.03), respectively. The most prevalent component of MetS was abdominal obesity (73.59), followed by reduced HDL cholesterol levels (44.83), elevated triglyceride (28.3), fasting glucose (35.34), and high blood pressure (32.64). In addition, the prevalence of MetS were 50.3, 70.4, 68.2, 65.7, and 60.8 among individuals with abdominal obesity, high triglyceride levels, hypertension, impaired fasting glucose, and low HDL-C levels, respectively. Results showed that 90% of the subjects displayed at least one component of MetS, and all MetS components were associated with major demographic characteristics of the study subjects. ConclusionsThe findings of this study indicate high prevalence of metabolic risk factors among study population. This study with a large sample size would contribute to establishment of efficient interventions and programs aimed at reducing the prevalence of MetS by health staff, supervisors and policymakers.