Abstract
Background: Solitary thyroid nodule is defined as discrete mass palpable in an otherwise apparently normal thyroid gland. Solitary nodule is the common presentation of thyroid disorders.
 Objective: This study aimed to look into the prevalence of malignancy in clinico-radiologically detected solitary thyroid nodule and to correlate the findings in pre-operative fine needle aspiration cytology(FNAC) and post-operative histopathological examination(HPE).
 Materials and Methods: A retrospective study was carried out in our Institute for a period of 6 months using the data obtained between 2018-2020 of patients who were clinically and radiologically diagnosed as solitary thyroid nodule in the Department of General Surgery.
 Results: Out of 30 cases of clinically detected solitary thyroid nodule 7(23.3%)cases was found to be malignant. The mean age of presentation was 41.2 years with male female ratio of 1:9. 25(83.3%)cases was reported as benign nodules according to pre-operative FNAC out of these 2(6.6%)cases turned out to be malignant on post-operative histopathological examination.
 Conclusion: It is concluded that from the present study the prevalence of malignancy in clinically detected solitary thyroid nodule is 23.3%. FNAC being sensitive, cost effective and reliable tool in the preoperative assessment of solitary thyroid nodules and HPE in post operative evaluation of clinical specimen both playing a vital role in management of solitary thyroid nodule thus helping in early diagnosis and proper surgical intervention.
Highlights
The most common clinical manifestation of thyroid disorders is usually a thyroid nodule
Solitary thyroid nodule is defined as discrete palpable mass in an otherwise apparently normal gland [1].Majority of diseases associated to thyroid gland may present as solitary thyroid nodule(STN).Solitary thyroid nodule are common among adults and accounts up to 4-7% of general population
Incidence of malignancy ranges from 10% to 30% in solitary thyroid nodule(STN).Studies have shown that the occurrence of malignancy is higher in case of solitary thyroid nodule compared to multinodular goitres
Summary
The most common clinical manifestation of thyroid disorders is usually a thyroid nodule. Solitary thyroid nodule is defined as discrete palpable mass in an otherwise apparently normal gland [1].Majority of diseases associated to thyroid gland may present as solitary thyroid nodule(STN).Solitary thyroid nodule are common among adults and accounts up to 4-7% of general population. It is seen more commonly in females(6.4%) compared to males(1.5%). Objective: This study aimed to look into the prevalence of malignancy in clinico-radiologically detected solitary thyroid nodule and to correlate the findings in pre-operative fine needle aspiration cytology(FNAC) and post-operative histopathological examination(HPE). FNAC being sensitive, cost effective and reliable tool in the preoperative assessment of solitary thyroid nodules and HPE in post operative evaluation of clinical specimen both playing a vital role in management of solitary thyroid nodule helping in early diagnosis and proper surgical intervention
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