Abstract

BackgroundThe use of substances is a growing concern in Ethiopia, and their impacts on younger generation have been a concern of different professionals. Even though students are at high-risk of substance abuse, there is lack of comprehensive evidence for policy decision on substance use among students. Therefore, the aim of this systematic review and meta-analysis was to estimate the prevalence of common substances among students in Ethiopia.MethodA comprehensive literature searches were done from biomedical databases: PubMed/Medline, African Journal Online, HINARI, Science Direct, and Google Scholar for article published until Dcember 31, 2017, and Addis Ababa Uiversity’s electronic library search of unpublished thesis and dissertations. Two authors autonomously selected studies, extracted data, and evaluated quality of studies. The prevalence of lifetime substances use was estimated using the random effects model. Q and I2 statistics were computed to measure the extents of heterogeneity.ResultsA total 676 study articles were identified from electronic databases, and 28 of them were included in meta-analysis. The analysis revealed that the lifetime prevalence of any substance use was 52.5% (95% CI 42.4–62.4%), khat 24.7% (95% CI 21.8–27.7%), alcohol 46.2% (95% CI 40.3–52.2%), and smoking cigarette 14.7% (95% CI 11.3–18.5%). Significant heterogeneity was observed but there was no significant publication bias. The lifetime prevalence of khat, alcohol, and cigarette smoking among high school vs university students was 22.5% (95% CI 15.2–30.7%) vs 25.1% (95% CI 21.9–28.5%), 41.4% (95% CI 22.1–62.1%) vs 47.8% (95% CI 39.9–55.7%), and 21.5% (95% CI 12.6–32.1%) vs 12.9% (95% CI 10.1–16.0%), respectively.ConclusionThis meta-analysis highlighted the extent of lifetime prevalence of any substance, khat, alcohol, and cigarettes smoking among students in Ethiopia. Significant percent of high school students have exposed to substances. Policy makers should devise and implement strictly binding regulation to curb widespread of substances around educational institution premises at national level. Priority should be given to intervention strategies that help delay first use of substance to prevent problems later in life. Besides, the problem warrants regular national-level educational institutions based studies focusing on the magnitude, trajectory, and consequences of substance use among students.Systematic review registration: PROSPERO CRD42018082635

Highlights

  • The use of substances is a growing concern in Ethiopia, and their impacts on younger generation have been a concern of different professionals

  • The analysis revealed that the lifetime prevalence of any substance use was 52.5%, khat 24.7%, alcohol 46.2%, and smoking cigarette 14.7%

  • This meta-analysis highlighted the extent of lifetime prevalence of any substance, khat, alcohol, and cigarettes smoking among students in Ethiopia

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Summary

Introduction

The use of substances is a growing concern in Ethiopia, and their impacts on younger generation have been a concern of different professionals. Psychoactive substances act on the central nervous system and change the activities of the brain These substances have wide range of effects, including short-term changes in perceptions, mood, consciousness, and behaviors [1]. Substances such as alcohol, khat, and tobacco are widely used [2, 3], and they are leading causes of human sufferings and become important public health and socioeconomic issue globally [4,5,6]. Smoking accounts for 11.5% of death and is among five leading risk factors of disability-adjusted lost life years (DALY) in 109 countries and territories in 2015 [9, 10]. Studies showed that chronic khat consumption causes severe neurological, psychiatric, cardiovascular, dental, gastrointestinal, and reproductive dysfunction [11,12,13,14,15,16], but it has adverse socioeconomic effects affecting other aspects of life [17]

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