Abstract
Background: Anemia in patients with cancer has been associated with poor outcomes. There are scarce data on the prevalence of iron and Vitamin B12 deficiencies and inflammatory anemia among treatment-naive patients in the Indian setting. Objectives: In this study, we aimed to evaluate the prevalence of anemia and iron and Vitamin B12 deficiencies along with inflammation in treatment-naive patients. Materials and Methods: This single-center cross-sectional study was conducted at the Indira Gandhi Institute of Medical Sciences (Patna, India) from July 2019 to December 2019. All patients registered in the Medical Oncology Department were offered testing for iron profile and serum Vitamin B12 and serum ferritin levels. Anemia was defined as hemoglobin level 300 mg/L, and Vitamin B12 level Results: We included 311 patients in the study, of which 167 (54%) were men. The median age of the cohort was 52 ± 15.9 years (range, 18–84). The prevalence of anemia was found to be 61% ± 2.7 (95% confidence interval, 55–66%). The mean hemoglobin level of the cohort was 9.86 ± 2.08 g/dl (range, 3–16). Of 311 patients, 21 (7%) had severe anemia (hemoglobin Conclusions: Two-thirds of our Indian patients with cancer are iron deficient, whereas half and one-third of them have Vitamin B12 deficiency and inflammation, respectively.
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