Abstract
Intracranial artery stenosis is the most common cause of acute ischemic stroke, especially among people in Asia. About its epidemiology, however little is understood. The goal of our research is to establish the prevalence of intracranial artery stenosis in patients with acute ischemic stroke in a tertiary care hospital. A descriptive cross-sectional study was done in 1006 acute ischemic stroke patients at Affiliated Zhongda Hospital, School of Medicine, Southeast University China from May 2018 to May 2019. Ethical approval was taken from the Ethical review committee of the institution. A convenient sampling method was done. Intracranial artery stenosis was diagnosed when evidence of acute ischemic stroke was found in the territory of approximately 2 50% stenosis identified by Transcranial Doppler ultrasound and confirmed by magnetic resonance angiography or computed tomography. Statistical analysis was done using the Statistical Package for the Social Sciences version 20. The prevalence of intracranial artery stenosis was found in 331 (32.90%) patients at 95% Confidence interval (0.24-0.42%). Among 331 cases the anterior circulation artery stenosis was present on 201 (19.98%) patients, followed by posterior circulation artery stenosis on 80 (7.95%) patients, then anterior plus posterior circulation artery stenosis on 50 (4.97%) patients. Intracranial artery stenosis is one of the most causes of acute ischemic stroke in China. The proportion of anterior circulation artery stenosis was higher than that in the posterior circulation.
Highlights
Intracranial artery stenosis is the most common cause of acute ischemic stroke, especially among people in Asia
Few studies have assessed that the extracranial stenosis is more prevalent in Asia.[4]
Exclusion criteria included patients with transient ischemic stroke, old infarction, a computed tomography (CT) scan of the head revealed intracerebral hemorrhage, artery stenosis caused by nonatherosclerotic factors such as arteritis, moyamoya disease, and arterial dissection or vasculitis, and cardioembolic stroke
Summary
Intracranial artery stenosis is the most common cause of acute ischemic stroke, especially among people in Asia. The goal of our research is to establish the prevalence of intracranial artery stenosis in patients with acute ischemic stroke in a tertiary care hospital. Stroke is one of the major causes of morbidity and mortality.[1] Intracranial artery stenosis (ICAS) is commonly associated with acute ischemic stroke (AIS) in Asians, Black, and Hispanic populations, which may account for up to half of ischemic cerebrovascular events in the Chinese populations.[2,3] few studies have assessed that the extracranial stenosis is more prevalent in Asia.[4]. ICAS can be diagnosed using various imaging methods. Among these methods, TCD is a safe, non-invasive, and cost-effective diagnostic method to determine ICAS.[5] The epidemiology of ICAS and its determinants may be more important in Asia than in the USA/Western
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