Prevalence of Impaired Oral Glucose Tolerance in Patients with Polycystic Ovarian Syndrome

Abstract

Objectives: To find the prevalence of PCOS in patients with menstrual irregularities and then to find the prevalence of impaired glucose tolerance among patients with PCOS. Study design: Descriptive cross sectional Place and Duration of Study: Department of Obstetrics and Gynecology, District Headquarter Hospital, Gujranwala from 1st November 2017 to 2nd May 2018. Methodology: Two hundred and twenty threepatients with menstrual irregularities were included In the study. Rotterdam classification criteria were used for proper identification of polycystic ovarian syndrome facilitated by clinical investigation. These patients were called for the oral GTT as explained in operational definitions. All blood samples were sent to our hospital laboratory. Results: Mean age of women was 32.54±7.54 years. Among women, 120 (53.8%) had family history of diabetes. Impaired glucose tolerance was confirmed in 55(24.7%) patients. Women who were diagnosed with PCOS among them impaired glucose tolerance was confirmed in 20(18.2%) patients. Conclusion: Glucose tolerance frequency was not significantly higher. However elderly and obese women had higher frequency of impaired glucose tolerance. Key words: PCOS, Menstrual irregularities, Impaired, Glucose, Tolerance