Prevalence of Hypothyroidism in PCOS in Jharkhand

Abstract

Polycystic ovarian syndrome and thyroid disorders are common endocrine disorders in females worldwide. These two problems are having many common features but are with very different etiopathogenesis. The increase in ovarian volume and cystic changes in ovaries have been reported in primary hypothyroidism due to disturbed ratio of FSH and LH. It is also seen that thyroid disorders are more common in women with PCOS as compared to the normal population may be due to other associated factors like insulin resistance, increased androgen secretion and obesity. There might be some common factors in individuals predisposing to both disorders but till date not any common pathophysiology is established between these two. The increased ovarian volume and fertility improves by administration of thyroxin apart from that it helps to control obesity and to some extent obesity related disorders. The diagnosis of hypothyroidism during adolescence will be helpful to improve especially fertility and PCOS related clinical conditions. The thyroid function study was done in PCOS patients between 18 to 35 years of age residing in Jharkhand and the results were compared with age matched healthy women. Having no medical problem or on contraceptive steroids females. Serum fasting free t3,free t4 and TSH levels were estimated. PCOS was confirmed by USG. Results of present study shows the prevalence of hypothyroidism in PCOS patient in Jharkhand.