Prevalence of Hypomagnesaemia in Asthma Patients-A Cross-Sectional Study

Abstract

Aim Magnesium intervenes in calcium transport mechanisms and intracellular phosphorylation reactions and so, it constitutes an important determinant of the contraction and relaxation state of bronchial smooth muscle. Present study was performed with an aim to know the prevalence of hypomagnesaemia in asthma patients. Materials and Method Sixty patients, who were attending department of respiratory medicine with steady asthma, were arbitrarily selected. They were evaluated clinically and their serum magnesium levels were calculated, than evaluated with the serum magnesium values of sixty non-asthmatic fit controls. Results Serum magnesium value among 1.5 and 2.5mg/dl was measured standard and every value underneath 1.5 mg/dl was measured as hypomagnesaemia. A total of 60 patients is evaluated with 60 fit persons. About 87.7% patients were establishing to have hypomagnesaemia and their serum magnesium value varies between 0.71 and 1.5 mg/dl. Remaining 12.3% patients had standard serum magnesium level. Conclusion Hypomagnesaemia is additional common in steady asthmatics than non-asthmatic Patients. Statistically significant association of hypomagnesaemia was observed with sternness of asthma. Future researches are desired by huge number of patients, and measuring Mg++ levels in RBC, WBC, or muscle cell in adding to serum Mg++ and this would be extremely obliging for evaluating the consequence of hypomagnesaemia in steady asthmatic patients.