Abstract
Hyperuricemia refers to an elevation in the serum uric acid concentration. The blood levels of uric acid are a function of the balance between the breakdown of purines & the rate of uric acid excretion. Theoretically, alterations in this balance many account for hyperuricemia. Prolonged hyperuricemia often associated with gout, is an important risk factor for damaged joints. The present study is undertaken with the aim to find out the prevalence of hyperuricemia by age & sex, to establish the statistically significant correlation between serum creatinine & triglyceride concentration with uric acid concentration & to study the relation between alcohol drinking & hyperuricemia in Morang District, by routine health examinations in the out Patients Department (OPD) of Nobel Medical College, Biratnagar from January 2012 to January 2013. The study reveals that 28.57% (male – 30.06%., female -26.61%) of patients have been suffering from hyperuricemia. It indirectly indicates hyperuricemia is very frequent in developing country like Nepal. The present study denoted that hyperuricemia is directly related to alcohol consumption in both male & female.DOI: http://dx.doi.org/10.3126/jonmc.v3i1.12228Journal of Nobel Medical College Vol. 3, No.1 Issue 6, 2014, Page: 1-6
Highlights
Hippocrates, in the fifth century B.C, recognized the distinctive clinical features of gouty arthrilitis, which he inscribed in the oldest recorded medical text[1]
The subjects were taken from Out Patients Department (OPD) of this hospital
NS = no statistical significance SD= Standard Deviation. This table showed that hyperuricemia is related to increased age, Creatinine and Triglyceride and it is not related to blood sugar
Summary
Hippocrates, in the fifth century B.C, recognized the distinctive clinical features of gouty arthrilitis, which he inscribed in the oldest recorded medical text[1]. The blood levels of uric acid are a function of the balance between the breakdown of purines and the rate of uric acid excretion Alterations in this balance may account for hyperuricemia, clinically. Among common disorders of elderly, high serum uric acid levels are found to be directly correlated to hypertension, heart disease, diabetes, kidney disease, dietary habits and nutrition. They eat foods that are high in purine such as red meat, beans, cabbage, cauliflower, alcohol and so on. The present study is to find out the prevalence of hyperuricemia among Nepali community by routine health examinations in the out patients Department (OPD) of Nobel Medical College, Biratnagar.
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