Abstract
Helicobacter Pylori is the most common chronic bacterial infection (acquired early childhood) in humans affecting 50% of the world population and much attention has not been paid to this. This study was carried out between February and October 2019 to test for the presence of Helicobacter Pylori antibody among asymptomatic individuals attending Federal Medical Center, Yenagoa, Bayelsa State. A total of 200 {114(57%) males, 86(43%) females} blood samples were collected at ramdom into Ethylene diamine tetraacetic acid (EDTA) bottles and immediately transported to the laboratory for analysis using Helicobacter pylori Serology rapid blood test kit. Age was stratified to allow for comparison because the entire outcome was age dependent. Chi square analysis was conducted for the categorical variable. Findings showed that out of 200 samples examined, 88(44%) forty (40 (45%) males and 48(55%) females were positive to Helicobacter pylori infection while 112(56%) were negative. Females of age range 24 -33 had the highest prevalence of 24 (27%) while male of age group 14 to 23 had 21(24%); females of 34 to 44 was 16(18%); 54-63 had 4(05%) and the least was 44 to 53 years with prevalence of 3(03%). There was a significant difference across the age group and socio-demographic characteristic at p-value = 0.0001 < 0.05 and p-value =0.002068 < 0.05, p-value = 0.000916 <0.05 respectively. Observations showed the higher prevalence in females (53%) than their males (47%) counterparts; likewise the infected individuals host this organism ignorantly and busy treating out of line. Study with more than one diagnostic technique is recommended to determine the presence of Helicobacter pylori, as rapid blood test is limited due to the presence of antibody in the serum for long after eradication. In conclusion, routine medical examination on Helicobacter pylori is encouraged among individuals in respective of age and status.
Highlights
Helicobacter pylori infection is known to disruptHelicobacter pylori (H. pylori) is a gram negative gastric secretion and impair its motility; it can spiral shaped bacterium with five flagella; it is an extend to other systemic organs especially the old microorganism that has been in existence since lower GI tract and associated with the symptoms after its discovery by Warren and Marshall. of irritableThe organism is an etiological agent of many bowels syndrome (IBS) as well as those of functional because of its the ability to invade the gastric dyspepsia (FD) (Hirotsuguet al., 2017)
The occurrence of placed beside gastric epithelial cells causing Helicobacter pylori infection is worldwide with chronic active gastritis; this can lead to gastric variations among countries and its building ulcer and gastrointestinal tract (GIT) discomfort. capacity is attributed to age, class, socioeconomic
Figure 1.0 depicts the pie chart of the number of positive and negative subjects to Helicobacter pylori infection Table 1.0 shows baseline characteristic of enrolled participant and H. pylori results Table 2.0 show the distribution of participant according to their age with their H. pylori outcome Table 3.0 show the relationship between sociodemographic characteristic and H. pylori result Figure 2.0 show positive and negative test result
Summary
Helicobacter pylori infection is known to disruptHelicobacter pylori (H. pylori) is a gram negative gastric secretion and impair its motility; it can spiral shaped bacterium with five flagella; it is an extend to other systemic organs especially the old microorganism that has been in existence since lower GI tract and associated with the symptoms after its discovery by Warren and Marshall. (abdominal pain or discomfort, etc.) of irritableThe organism is an etiological agent of many bowels syndrome (IBS) as well as those (satiation, diseases ranging from Upper Gastrointestinal fullness, epigastric pain, etc.) of functional because of its the ability to invade the gastric dyspepsia (FD) (Hirotsuguet al., 2017). Despite the discovery of Helicobacter pylori and understanding of its etiology, important data generated from the organism investigations with respect to pathophysiology in its host body has not been interpreted into clinical practice for proper comprehension and documentation Many individuals harbor this microorganism ignorantly and are busy treating malaria and other irrelevant infections without having the knowledge of their actual problem especially in the developing countries such as Nigeria. Pylori infection across different clinical conditions at Federal Medical Center Yenagoa and Asymptomatic subjects in Amassoma community was carried out and compared the differences in the statistical significance across different age group, social demographic characteristic of the subjects with positive blood test to that of negative
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