Abstract

Point prevalence surveys of healthcare-associated infections (HAI) and antimicrobial use in the European Union and European Economic Area (EU/EEA) from 2016 to 2017 included 310,755 patients from 1,209 acute care hospitals (ACH) in 28 countries and 117,138 residents from 2,221 long-term care facilities (LTCF) in 23 countries. After national validation, we estimated that 6.5% (cumulative 95% confidence interval (cCI): 5.4–7.8%) patients in ACH and 3.9% (95% cCI: 2.4–6.0%) residents in LTCF had at least one HAI (country-weighted prevalence). On any given day, 98,166 patients (95% cCI: 81,022–117,484) in ACH and 129,940 (95% cCI: 79,570–197,625) residents in LTCF had an HAI. HAI episodes per year were estimated at 8.9 million (95% cCI: 4.6–15.6 million), including 4.5 million (95% cCI: 2.6–7.6 million) in ACH and 4.4 million (95% cCI: 2.0–8.0 million) in LTCF; 3.8 million (95% cCI: 3.1–4.5 million) patients acquired an HAI each year in ACH. Antimicrobial resistance (AMR) to selected AMR markers was 31.6% in ACH and 28.0% in LTCF. Our study confirmed a high annual number of HAI in healthcare facilities in the EU/EEA and indicated that AMR in HAI in LTCF may have reached the same level as in ACH.

Highlights

  • In 2016, the European Centre for Disease Prevention and Control (ECDC) estimated that the burden of six main types of healthcare-associated infection)expressed in disability-adjusted life years (DALYs) in the European Union and European Economic Area (EU/EEA) was higher than the combined burden of 31 other infectious diseases under surveillance by ECDC [1,2].The estimated number of healthcare-associated infections (HAI) used in the study was based on the data of the first ECDC point prevalence survey (PPS) of HAI and antimicrobial use in acute care hospitals (ACH)from 2011 to 2012 [3] and did not take into accountHAI occurring in other healthcare facilities

  • ECDC had previously estimated that the number of residents with an HAI on any given day in European long-term care facilities (LTCF) was of the same order www.eurosurveillance.org

  • This study reports, to our knowledge, the most accurate and robust estimates of the total number of HAI in www.eurosurveillance.org healthcare facilities in the EU/EEA to date, and confirms that HAI, and Antimicrobial resistance (AMR) in bacteria responsible for HAI, represent a significant healthcare issue and public health challenge for the EU/EEA

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Summary

Introduction

In 2016, the European Centre for Disease Prevention and Control (ECDC) estimated that the burden of six main types of healthcare-associated infection (healthcare-associated pneumonia, urinary tract infection, surgical site infection, Clostridium difficile infection, neonatal sepsis and primary bloodstream infection))expressed in disability-adjusted life years (DALYs) in the European Union and European Economic Area (EU/EEA) was higher than the combined burden of 31 other infectious diseases under surveillance by ECDC [1,2].The estimated number of healthcare-associated infections (HAI) used in the study was based on the data of the first ECDC point prevalence survey (PPS) of HAI and antimicrobial use in acute care hospitals (ACH)from 2011 to 2012 [3] and did not take into accountHAI occurring in other healthcare facilities. In 2016, the European Centre for Disease Prevention and Control (ECDC) estimated that the burden of six main types of healthcare-associated infection (healthcare-associated pneumonia, urinary tract infection, surgical site infection, Clostridium difficile infection, neonatal sepsis and primary bloodstream infection)). EEA) was higher than the combined burden of 31 other infectious diseases under surveillance by ECDC [1,2]. The estimated number of healthcare-associated infections (HAI) used in the study was based on the data of the first ECDC point prevalence survey (PPS) of HAI and antimicrobial use in acute care hospitals (ACH). ECDC had previously estimated that the number of residents with an HAI on any given day in European long-term care facilities (LTCF) was of the same order www.eurosurveillance.org Hungary Iceland Ireland NP In PPS sample

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