Prevalence of HAV Ab IgG and anti-HBs Ab and HBV vaccination history of adults in Jeju

Abstract

Recently, the incidence of acute hepatitis A was reported to be increased. The prevalence of hepatitis A is associated with socioeconomic and hygiene status. This study is to investigate theseroprevalence of hepatitis A virus antibody and hepatitis B virus antibody in Jeju province and investigate vaccination history of hepatitis B virus. From June 2008 to March 2009, we tested HAV Ab IgG of 468 healthy adult subjects who visited the health promotion center in Jeju National University Hospital and reviewed a total of 929 questionnaire about of HBV vaccination history and tested anti-HBs Ab of 1000 subjects. According to gender, the seropositive rate of HAV Ab IgG was 91.5% inmen, 90.5% in women, there was no significant gap between gender groups. According to age, 9.5% under 29 years, 85.9% in 30-39 years, 97.1 % in 40-49 years, 100% in above 50 years. The seropositive rate was on the increase with age. The prevalence rate of anti-HBs Ab was decreased with age (82.6% in under 29 years. 66.5% in 30-39 years, 70.5% in 40-49 years, 63.7% in 50-59 years, 58.3% above 60 years). About history and frequency of HBV vaccination subjects didn't know vaccination history as age decreased, the HBV vaccination rale in subjects who knew vaccination history were significantly increased with age. Regardless of age, the prevalence rate of anti-HBs Ab was higher in subjects who had vaccination history. The prevalence of HAV Ab IgG below age 30 in Jeju is quite low, so HAV vaccination below age 30 would be necessary. Younger subjects didn't know about their HBV vaccination history and subjects who had HBV vaccination history tended to show higher prevalence rate of anti-HBV antibody. So education about importance of knowing aboug vaccination history when childhood would be necessary.