Prevalence of group B streptococcus colonisation and pregnancy outcomes of pregnant women at Hanoi Obstetrics and Gynecology Hospital

Abstract

Objectives: To determine the prevalence of maternal group B streptococcus (GBS) colonisation and pregnancy results of pregnant women at Hanoi Obstetrics and Gynecology Hospital. Materials and methods: Retrospective descriptive with 537 pregnant women delivered at the Hanoi Obstetrics and Gynecology Hospital in 2021, GBS was detected based on culture, isolation, and identification of bacteria from the vagina-rectum samples at 36-37+6 weeks gestation. Results: The prevalence of maternal GBS colonisation was 18.1%. 87.5% of GBS colonisations were applied to intrapartum antibiotic prophylaxis during labour or ruptured membranes. Diabetes increased the risk of carrying GBS (OR=2.3, 95%CI: 1.17-4.34). Maternal GBS colonisation increased the risk of rupture of membranes (OR 3.09, 95%CI: 1.95-4.85) and antibiotic treatment of newborns (OR=3.39, 95%CI: 1.05-10.92). However, there was no increased risk for cesarean section or postpartum infection (p>0.05). Maternal GBS colonisation with intrapartum antibiotic prophylaxis has not increased the risk for early neonatal (OR=0.55, 95%CI: 0.06-5.44). Conclusion: The prevalence of maternal GBS colonisation was 18.1%. Pregnant women carrying GBS treated with intrapartum antibiotic prophylaxis did not increase the risk of maternal adverse pregnancy outcomes and early neonatal infection.