Abstract
The present study aims to explore the prevalence of genotype 3a under hepatitis C virus (HCV) infections among all the provinces of Pakistan. It is alarming to note that Pakistan stands in the second position for having a large number of cases of HCV every year. Six major genotypes characterize HCV. To study the overall prevalence of HCV and its associated genotype 3a in all the provinces of Pakistan, a systematic review and meta-analysis were performed using STATA version 14.2. The published studies conducted in all the regions of Pakistan reported the incidence of HCV genotype 3a were shortlisted. The pooled summary estimates were calculated along with their confidence interval by using the "Metaprop" command. The literature review showed that the prevalence of HCV genotype 3a is most common in all the provinces of Pakistan. It is revealed that the prevalence of HCV genotype 3a was 86.46% in Punjab, which is the highest among all the regions.
Highlights
Data on the prevalence of hepatitis C virus (HCV) genotype 3a was recorded for different regions
The meta-analysis results revealed that the pooled estimate for the prevalence of HCV genotype 3a in KPK is 0.56, implying that 56% of its population is infected with HCV genotype 3a
The present research was conducted to highlight the prevalence of HCV genotype 3a in Pakistan
Summary
Hepatitis C virus (HCV) is a worldwide medical problem influencing approximately 3% of people worldwide [1]. South Africa and Australia are more infected regions in terms of genotype 3's prevalence [10]. In Central Africa and Egypt, the most prevalent type of HCV virus is genotype 4 [11,12]. Untrained medical staff plays a significant role in HCV transference for genotype 3 (p
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