Abstract

Background Mortality and morbidity in patients with diabetes mellitus (DM) are attributed to both microvascular and macrovascular complications. However, there is a significant amount of variation in the primary studies on DM regarding the prevalence of erectile dysfunction (ED) in Africa. Therefore, this study was aimed to estimate the pooled prevalence of ED patients with DM and its association with body mass index (BMI) and glycated hemoglobin in Africa. Methods PubMed, Web of Science, Cochrane Library, Scopus, PsycINFO, African Journals Online, and Google Scholar were searched for studies that looked at ED in DM patients. A funnel plot and Egger's regression test were used to determine publication bias. The I2 statistic was used to check heterogeneity between the studies. DerSimonian and Laird random-effects model was applied to estimate the pooled effect size. The subgroup and meta-regression analyses were conducted by country, sample size, and year of publication. Sensitivity analysis was deployed to see the effect of a single study on the overall estimation. STATA version 14 statistical software was used for the meta-analysis. Result A total of 13 studies with 3,501 study participants were included in this study. We estimated that the pooled prevalence of ED in patients with DM in Africa was 71.45% (95% CI: 60.22–82.69). Diabetic patients whose BMI was ≥30 kg/m2 were 1.26 times more likely to develop ED (AOR = 1.26; 95% CI: 0.73–2.16) and whose glycated hemoglobin was <7% were 7% less likely to develop ED (AOR = 0.93; 95% CI: 0.5–5.9), although they were not significantly associated with ED. Conclusions The prevalence of ED in DM patients in Africa remains high. Therefore, situation-based interventions and country context-specific preventive strategies should be developed to reduce the prevalence of ED among patients with DM.

Highlights

  • Diabetes is a major public health problem, increasingly affecting millions of people across the globe [1]

  • About 1,617 studies were found from seven international databases, and the remaining 5 were through a manual search. e databases included PubMed (43), Scopus (28), Google Scholar (800), Web of Science (317), Cochrane Library (3), PsycINFO (19), and African Journals Online (407)

  • Our estimated prevalence of erectile dysfunction (ED) in diabetes mellitus (DM) patients in Africa is substantially higher than that reported in a systematic review and meta-analysis conducted at the global level, which sets the prevalence at 52.5% [50]. is variation could be justified by the different diagnostic criteria for ED, differences in methodology, and population characteristics

Read more

Summary

Introduction

Diabetes is a major public health problem, increasingly affecting millions of people across the globe [1]. Mortality and morbidity in patients with DM are often the result of both micro- and macrovascular complications. ED is the inability to achieve and maintain an erection sufficient to permit satisfactory sexual intercourse [6] It may result from psychological, neurologic, hormonal, or arterial impairment or from a combination of these factors [7]. Mortality and morbidity in patients with diabetes mellitus (DM) are attributed to both microvascular and macrovascular complications. There is a significant amount of variation in the primary studies on DM regarding the prevalence of erectile dysfunction (ED) in Africa. Erefore, this study was aimed to estimate the pooled prevalence of ED patients with DM and its association with body mass index (BMI) and glycated hemoglobin in Africa. DerSimonian and Laird random-effects model was applied to estimate the pooled effect size

Objectives
Methods
Results
Discussion
Conclusion

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.